A possible upgrade for the pumpkin bombs in the Raimiverse. Scales to all the 9-As.
Here. The pumpkin bomb disintegrates size people.
Method 1[]
According to FanofRPG's calc, it takes 295 258 711.05 Joules to vaporize a human being. Green Goblin's pumpkin bomb disintegrated six people. Although the bones seemed to be not vaporized, they actually turned to powder as well.
295258711.05*6 = 1.7715522663e9 Joules, 423.41 kg of TNT, or Building level
Method 2[]
Using Inverse Square Law.

Head of the woman: 24 px or 20 cm
Panel height: 220 px
2atan(24/(220/tan(70/2))) = 5.91784262 degrees
According to the Angular Size Calculator that is 1.9347 m.
The explosion is restricted downwards as it is on the floor, so we'll assume a hemisphere.
1.7715522663e9*2*(4*pi*(1.9347)^2) = 1.6665605334587487294e11 Joules, 39.83 Tons of TNT, City Block level