Note: Since both of these characters are Small Town level and Massively Hypersonic speed, I could do this fight at last. Unfortunately this fight won't be added since I'm using my own character stats here, so Fun and Games board we go!~
1. This is Spider-Man at his strongest from Earth-616 Marvel Comics without any injuries; whereas this is Meruem at his strongest from Hunter x Hunter without any injuries.
2. Spider-Man in prime, has Chi, Spider Physiology, Upgrades, Queen's Mutation, The Other Evolution, Mindwipe after "Brand New Day", Doctor Octopus, Enhanced Spider-Sense & Symbiotes, got Genetic Dampener, The Enervator, Webware, Web-Shooters, Web Cartridges, Nose-Filters, Utility Belt, Anti-Metal Spider Tracers, Explosive Spider-Tracers, Spider-Tracers, Spider-Signal, Ice Capsules, Avengers Identicard, Anti-Magnetic Gadgets, Anti-Magnetic Inverter, Anti-Sonic Inverter, Anti-Sonic Earplugs & Spider-Armor MK IV, and rides Spider-Glider, Spider-Mobile & Hydro-Spider.
3. Meruem in prime, has Nen, and is Pre-Poor Man's Rose.
Peter is gonna smack the shit out of this man. With all the crazy abilities he has plus his broken Spider-Sense, plus the fact that with no training whatsoever he was able to match one of the greatest Martial Artists in Marvel (Shang Chi) means he's probably gonna run circles around Meruem.
Meruem exists above humanity, clearly meaning that every human in HXH combined is fodder to him, and since Meruem is called the King, clearly he is the strongest creature in HXH and will stay that way. The HXH world is actually equal to the universe in size because we don't see space, and there are monsters comparable in size to it, therefor Meruem is AT LEAST multi-galaxy level. He stomps the Marvel franchise anyways because he was written to only be killed by poisoning from the Rose Bomb.