Self-Destruction is the ability to detonate oneself in an attempt to kill their foe with the blast. This process is almost invariably fatal to the user, but some characters are capable of surviving their own self-destruction techniques.
- Chiaotzu, Saibamen, Vegeta, Son Goku (Dragon Ball GT), Cell, Android 16, Android 17, and Android 18 (Dragon Ball)
- Deidara (Naruto)
- Pokémon that can learn "Self-Destruct" or "Explosion (Pokémon)
- Nitro (Marvel Comics)
- Creeper (Minecraft)
- Sentry Buster (Team Fortress)
- YoRHa No.2 Type B (NieR: Automata)